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Am J Physiol Gastrointest Liver Physiol 232: G294-G297, 1977;
0193-1857/77 $5.00
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AJP: Gastrointestinal and Liver Physiology, Vol 232, Issue 3, G294-G297
Copyright © 1977 by American Physiological Society

ARTICLES

Uptake of K+ by frog gastric mucosa from submucosal side and acid secretory rate

N Takeguchi, I Horikoshi, and M Hattori

The K+ content in frog gastric mucosa (K+) was measured as a function of the submucosal K+ concentration ([K+sm]) in the absence of K+ on the mucosal side. The (K+) in HCO3- buffer with 95% O2-5% CO2 gas showed that the removal of external K+ induced a 27% K+ loss from the control value of 5 mM K+sm, that there was no linear relation between (K+) and [K+sm, and that the change in the (K+) versus the [K+sm] was hyperbolic, indicating that there are two different types of K+ in the mucosa: bound and free K+.





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