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Am J Physiol Gastrointest Liver Physiol 246: G471-G476, 1984;
0193-1857/84 $5.00
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AJP - Gastrointestinal and Liver Physiology, Vol 246, Issue 5 471-G476, Copyright © 1984 by American Physiological Society

ARTICLES

Cholecystokinin receptor antagonists

J. D. Gardner and R. T. Jensen

Since 1979 three classes of cholecystokinin receptor antagonists have been described: 1) derivatives of cyclic nucleotides, 2) derivatives of amino acids, and 3) C-terminal fragments or partial sequences of cholecystokinin. These various antagonists share a number of common features, such as their specific, reversible, and competitive actions, but they vary in the potency with which they inhibit the actions of cholecystokinin.




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