THEMES:

A. S. Giraud, C. Jackson, T. R. Menheniott, and L. M. Judd

Differentiation of the Gastric Mucosa IV. Role of trefoil peptides and IL-6 cytokine family signaling in gastric homeostasis
Am J Physiol Gastrointest Liver Physiol 292: G1-G5, 2007. First published August 24, 2006; doi:10.1152/ajpgi.00382.2006 [Abstract] [Full Text] [PDF]  

Ian R. Sanderson and W. Allan Walker

TLRs in the Gut I. The role of TLRs/Nods in intestinal development and homeostasis
Am J Physiol Gastrointest Liver Physiol 292: G6-G10, 2007. First published July 13, 2006; doi:10.1152/ajpgi.00275.2006 [Abstract] [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Oliver Goetze, Andreas Steingoetter, Dieter Menne, Ivo R. van der Voort, Monika A. Kwiatek, Peter Boesiger, Dominik Weishaupt, Miriam Thumshirn, Michael Fried, and Werner Schwizer

The effect of macronutrients on gastric volume responses and gastric emptying in humans: a magnetic resonance imaging study
Am J Physiol Gastrointest Liver Physiol 292: G11-G17, 2007. First published August 24, 2006; doi:10.1152/ajpgi.00498.2005 [Abstract] [Full Text] [PDF]  

Kathy Hormi-Carver, Linda A. Feagins, Stuart J. Spechler, and Rhonda F. Souza

All trans-retinoic acid induces apoptosis via p38 and caspase pathways in metaplastic Barrett's cells
Am J Physiol Gastrointest Liver Physiol 292: G18-G27, 2007. First published August 24, 2006; doi:10.1152/ajpgi.00237.2006 [Abstract] [Full Text] [PDF]  

MUCOSAL BIOLOGY:

Hua Yang, Xiaoyi Sun, Emir Q. Haxhija, and Daniel H. Teitelbaum

Intestinal epithelial cell-derived interleukin-7: a mechanism for the alteration of intraepithelial lymphocytes in a mouse model of total parenteral nutrition
Am J Physiol Gastrointest Liver Physiol 292: G84-G91, 2007. First published January 1, 2007; doi:10.1152/ajpgi.00192.2006 [Abstract] [Full Text] [PDF]  

Sigrid A. Rajasekaran, Sonali P. Barwe, Jegan Gopal, Sergey Ryazantsev, Eveline E. Schneeberger, and Ayyappan K. Rajasekaran

Na-K-ATPase regulates tight junction permeability through occludin phosphorylation in pancreatic epithelial cells
Am J Physiol Gastrointest Liver Physiol 292: G124-G133, 2007. First published September 7, 2006; doi:10.1152/ajpgi.00297.2006 [Abstract] [Full Text] [PDF]  

Tadayoshi Takeuchi, Keisuke Tanaka, Hidemitsu Nakajima, Minoru Matsui, and Yasu-Taka Azuma

M₂ and M₃ muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum: findings obtained with muscarinic-receptor knockout mouse
Am J Physiol Gastrointest Liver Physiol 292: G154-G164, 2007. First published September 28, 2006; doi:10.1152/ajpgi.00173.2006 [Abstract] [Full Text] [PDF]  

Adam J. Moeser, Carin Vander Klok, Kathleen A. Ryan, Jenna G. Wooten, Dianne Little, Vanessa L. Cook, and Anthony T. Blikslager

Stress signaling pathways activated by weaning mediate intestinal dysfunction in the pig
Am J Physiol Gastrointest Liver Physiol 292: G173-G181, 2007. First published August 10, 2006; doi:10.1152/ajpgi.00197.2006 [Abstract] [Full Text] [PDF]  

M. Kidd, I. M. Modlin, G. N. Eick, R. L. Camp, and S. M. Mane

Role of CCN2/CTGF in the proliferation of Mastomys enterochromaffin-like cells and gastric carcinoid development
Am J Physiol Gastrointest Liver Physiol 292: G191-G200, 2007. First published August 31, 2006; doi:10.1152/ajpgi.00131.2006 [Abstract] [Full Text] [PDF]  

Michael A. Helmrath, Jerry J. Fong, Christopher M. Dekaney, and Susan J. Henning

Rapid expansion of intestinal secretory lineages following a massive small bowel resection in mice
Am J Physiol Gastrointest Liver Physiol 292: G215-G222, 2007. First published August 17, 2006; doi:10.1152/ajpgi.00188.2006 [Abstract] [Full Text] [PDF]  

Jack C. Reidling, Svetlana M. Nabokina, and Hamid M. Said

Molecular mechanisms involved in the adaptive regulation of human intestinal biotin uptake: a study of the hSMVT system
Am J Physiol Gastrointest Liver Physiol 292: G275-G281, 2007. First published September 7, 2006; doi:10.1152/ajpgi.00327.2006 [Abstract] [Full Text] [PDF]  

Stephen J. Keely, Michael M. Scharl, Lone S. Bertelsen, Lee R. Hagey, Kim E. Barrett, and Alan F. Hofmann

Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: structure-activity relationships
Am J Physiol Gastrointest Liver Physiol 292: G290-G297, 2007. First published August 10, 2006; doi:10.1152/ajpgi.00076.2006 [Abstract] [Full Text] [PDF]  

C. Caballero-Franco, K. Keller, C. De Simone, and K. Chadee

The VSL#3 probiotic formula induces mucin gene expression and secretion in colonic epithelial cells
Am J Physiol Gastrointest Liver Physiol 292: G315-G322, 2007. First published September 14, 2006; doi:10.1152/ajpgi.00265.2006 [Abstract] [Full Text] [PDF]  

S. F. Drake, E. H. Morgan, C. E. Herbison, R. Delima, R. M. Graham, A. C. G. Chua, P. J. Leedman, R. E. Fleming, B. R. Bacon, J. K. Olynyk, and D. Trinder

Iron absorption and hepatic iron uptake are increased in a transferrin receptor 2 (Y245X) mutant mouse model of hemochromatosis type 3
Am J Physiol Gastrointest Liver Physiol 292: G323-G328, 2007. First published August 24, 2006; doi:10.1152/ajpgi.00278.2006 [Abstract] [Full Text] [PDF]  

Jaladanki N. Rao, Lan Liu, Tongtong Zou, Bernard S. Marasa, Dessy Boneva, Shelley R. Wang, Debra L. Malone, Douglas J. Turner, and Jian-Ying Wang

Polyamines are required for phospholipase C-₁ expression promoting intestinal epithelial restitution after wounding
Am J Physiol Gastrointest Liver Physiol 292: G335-G343, 2007. First published September 14, 2006; doi:10.1152/ajpgi.00282.2006 [Abstract] [Full Text] [PDF]  

Vicky De Preter, Tom Vanhoutte, Geert Huys, Jean Swings, Luc De Vuyst, Paul Rutgeerts, and Kristin Verbeke

Effects of Lactobacillus casei Shirota, Bifidobacterium breve, and oligofructose-enriched inulin on colonic nitrogen-protein metabolism in healthy humans
Am J Physiol Gastrointest Liver Physiol 292: G358-G368, 2007. First published September 21, 2006; doi:10.1152/ajpgi.00052.2006 [Abstract] [Full Text] [PDF]  

Waddah A. Alrefai, Fadi Annaba, Zaheer Sarwar, Alka Dwivedi, Seema Saksena, Amika Singla, Pradeep K. Dudeja, and Ravinder K. Gill

Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: role of sterol regulatory element binding protein 2
Am J Physiol Gastrointest Liver Physiol 292: G369-G376, 2007. First published September 28, 2006; doi:10.1152/ajpgi.00306.2006 [Abstract] [Full Text] [PDF]  

INFLAMMATION/IMMUNITY/MEDIATORS:

Nachiket J. Patel, Olga Zaborina, Licheng Wu, Yingmin Wang, Donald J. Wolfgeher, Vesta Valuckaite, Mae J. Ciancio, Jonathan E. Kohler, Olga Shevchenko, Sean P. Colgan, Eugene B. Chang, Jerrold R. Turner, and John C. Alverdy

Recognition of intestinal epithelial HIF-1 activation by Pseudomonas aeruginosa
Am J Physiol Gastrointest Liver Physiol 292: G134-G142, 2007. First published August 10, 2006; doi:10.1152/ajpgi.00276.2006 [Abstract] [Full Text] [PDF]  

Jia Sun and Madhav Bhatia

Blockade of neurokinin-1 receptor attenuates CC and CXC chemokine production in experimental acute pancreatitis and associated lung injury
Am J Physiol Gastrointest Liver Physiol 292: G143-G153, 2007. First published July 27, 2006; doi:10.1152/ajpgi.00271.2006 [Abstract] [Full Text] [PDF]  

Silvia Melgar, Mikael Bjursell, Anna-Karin Gerdin, Lennart Svensson, Erik Michaëlsson, and Mohammad Bohlooly-Y

Mice with experimental colitis show an altered metabolism with decreased metabolic rate
Am J Physiol Gastrointest Liver Physiol 292: G165-G172, 2007. First published July 13, 2006; doi:10.1152/ajpgi.00152.2006 [Abstract] [Full Text] [PDF]  

M. Neunlist, P. Aubert, S. Bonnaud, L. Van Landeghem, E. Coron, T. Wedel, P. Naveilhan, A. Ruhl, B. Lardeux, T. Savidge, F. Paris, and J. P. Galmiche

Enteric glia inhibit intestinal epithelial cell proliferation partly through a TGF-₁-dependent pathway
Am J Physiol Gastrointest Liver Physiol 292: G231-G241, 2007. First published January 19, 2006; doi:10.1152/ajpgi.00276.2005 [Abstract] [Full Text] [PDF]  

Cynthia C. Wetzel, Mike A. Leonis, Arlene Dent, Meredith A. Olson, Angela M. Longmeier, Paul A. Ney, Greg P. Boivin, Sarah A. Kader, Charles C. Caldwell, Sandra J. F. Degen, and Susan E. Waltz

Short-form Ron receptor is required for normal IFN- production in concanavalin A-induced acute liver injury
Am J Physiol Gastrointest Liver Physiol 292: G253-G261, 2007. First published September 28, 2006; doi:10.1152/ajpgi.00134.2006 [Abstract] [Full Text] [PDF]  

Hitomi Seino, Haruyasu Ueda, Masahiro Kokai, Noriko M. Tsuji, Shinichiro Kashiwamura, Yoshio Morita, and Haruki Okamura

IL-18 mediates the formation of stress-induced, histamine-dependent gastric lesions
Am J Physiol Gastrointest Liver Physiol 292: G262-G267, 2007. First published September 7, 2006; doi:10.1152/ajpgi.00588.2005 [Abstract] [Full Text] [PDF]  

Takeshi Matsutani, Shih-Ching Kang, Masao Miyashita, Koji Sasajima, Mashkoor A. Choudhry, Kirby I. Bland, and Irshad H. Chaudry

Liver cytokine production and ICAM-1 expression following bone fracture, tissue trauma, and hemorrhage in middle-aged mice
Am J Physiol Gastrointest Liver Physiol 292: G268-G274, 2007. First published September 7, 2006; doi:10.1152/ajpgi.00313.2006 [Abstract] [Full Text] [PDF]  

Claudio Csillag, Ole Haagen Nielsen, Rehannah Borup, Finn Cilius Nielsen, and Jørgen Olsen

Clinical phenotype and gene expression profile in Crohn's disease
Am J Physiol Gastrointest Liver Physiol 292: G298-G304, 2007. First published September 7, 2006; doi:10.1152/ajpgi.00321.2006 [Abstract] [Full Text] [PDF]  

HORMONES AND SIGNALING:

Yanna Cao, Lu Chen, Weili Zhang, Yan Liu, Harry T. Papaconstantinou, Craig R. Bush, Courtney M. Townsend, Jr., E. Aubrey Thompson, and Tien C. Ko

Identification of apoptotic genes mediating TGF-/Smad3-induced cell death in intestinal epithelial cells using a genomic approach
Am J Physiol Gastrointest Liver Physiol 292: G28-G38, 2007. First published August 10, 2006; doi:10.1152/ajpgi.00437.2005 [Abstract] [Full Text] [PDF]  

Zhigang Chen, Thomas L. Eggerman, and Amy P. Patterson

ApoB mRNA editing is mediated by a coordinated modulation of multiple apoB mRNA editing enzyme components
Am J Physiol Gastrointest Liver Physiol 292: G53-G65, 2007. First published August 17, 2006; doi:10.1152/ajpgi.00118.2006 [Abstract] [Full Text] [PDF]  

Do Y. Lim, Yoonhwa Jeong, Angela L. Tyner, and Jung H. Y. Park

Induction of cell cycle arrest and apoptosis in HT-29 human colon cancer cells by the dietary compound luteolin
Am J Physiol Gastrointest Liver Physiol 292: G66-G75, 2007. First published August 10, 2006; doi:10.1152/ajpgi.00248.2006 [Abstract] [Full Text] [PDF]  

Sylvie Huybers, Ton H. J. Naber, René J. M. Bindels, and Joost G. J. Hoenderop

Prednisolone-induced Ca²⁺ malabsorption is caused by diminished expression of the epithelial Ca²⁺ channel TRPV6
Am J Physiol Gastrointest Liver Physiol 292: G92-G97, 2007. First published August 10, 2006; doi:10.1152/ajpgi.00317.2006 [Abstract] [Full Text] [PDF]  

Sungwon Choi, Mike Lee, Amy L. Shiu, Sek Jin Yo, and Gregory W. Aponte

Identification of a protein hydrolysate responsive G protein-coupled receptor in enterocytes
Am J Physiol Gastrointest Liver Physiol 292: G98-G112, 2007. First published August 24, 2006; doi:10.1152/ajpgi.00295.2006 [Abstract] [Full Text] [PDF]  

Shizhong Zheng and Anping Chen

Disruption of transforming growth factor- signaling by curcumin induces gene expression of peroxisome proliferator-activated receptor- in rat hepatic stellate cells
Am J Physiol Gastrointest Liver Physiol 292: G113-G123, 2007. First published September 7, 2006; doi:10.1152/ajpgi.00200.2006 [Abstract] [Full Text] [PDF]  

Lauren Taglia, Damien Matusiak, Kristina A. Matkowskyj, and Richard V. Benya

Gastrin-releasing peptide mediates its morphogenic properties in human colon cancer by upregulating intracellular adhesion protein-1 (ICAM-1) via focal adhesion kinase
Am J Physiol Gastrointest Liver Physiol 292: G182-G190, 2007. First published August 17, 2006; doi:10.1152/ajpgi.00201.2006 [Abstract] [Full Text] [PDF]  

Carmina Montoliu, Blanca Piedrafita, Miguel A. Serra, Juan A. del Olmo, José M. Rodrigo, and Vicente Felipo

A single transient episode of hyperammonemia induces long-lasting alterations in protein kinase A
Am J Physiol Gastrointest Liver Physiol 292: G305-G314, 2007; doi:10.1152/ajpgi.00100.2006 [Abstract] [Full Text] [PDF]  

María E. Sabbatini, Marcelo S. Vatta, Carlos A. Davio, and Liliana G. Bianciotti

Atrial natriuretic factor negatively modulates secretin intracellular signaling in the exocrine pancreas
Am J Physiol Gastrointest Liver Physiol 292: G349-G357, 2007. First published September 14, 2006; doi:10.1152/ajpgi.00163.2006 [Abstract] [Full Text] [PDF]  

NEUROREGULATION AND MOTILITY:

Muxin Wei, Kotoyo Fujiki, Eiji Ando, Sumin Zhang, Tsuyoshi Ozaki, Hiroshi Ishiguro, Takaharu Kondo, Kiyoshi Nokihara, Victor Wray, and Satoru Naruse

Identification of key residues that cause differential gallbladder response to PACAP and VIP in the guinea pig
Am J Physiol Gastrointest Liver Physiol 292: G76-G83, 2007. First published August 10, 2006; doi:10.1152/ajpgi.00279.2006 [Abstract] [Full Text] [PDF]  

Ingrid M. de Zwart, Jeoffrey J. L. Haans, Paul Verbeek, Paul H. C. Eilers, Albert de Roos, and Ad A. M. Masclee

Gastric accommodation and motility are influenced by the barostat device: assessment with magnetic resonance imaging
Am J Physiol Gastrointest Liver Physiol 292: G208-G214, 2007. First published August 3, 2006; doi:10.1152/ajpgi.00151.2006 [Abstract] [Full Text] [PDF]  

Christopher Andrews, Adil E. Bharucha, Barb Seide, and A. R. Zinsmeister

Rectal sensorimotor dysfunction in women with fecal incontinence
Am J Physiol Gastrointest Liver Physiol 292: G282-G289, 2007. First published August 31, 2006; doi:10.1152/ajpgi.00176.2006 [Abstract] [Full Text] [PDF]  

Ibrahim Dogan, Valmik Bhargava, Jianmin Liu, and Ravinder K. Mittal

Axial stretch: a novel mechanism of the lower esophageal sphincter relaxation
Am J Physiol Gastrointest Liver Physiol 292: G329-G334, 2007. First published October 5, 2006; doi:10.1152/ajpgi.00351.2006 [Abstract] [Full Text] [PDF]  

Monica Verma-Gandhu, Elena F. Verdu, Daniel Cohen-Lyons, and Stephen M. Collins

Lymphocyte-mediated regulation of -endorphin in the myenteric plexus
Am J Physiol Gastrointest Liver Physiol 292: G344-G348, 2007. First published September 7, 2006; doi:10.1152/ajpgi.00318.2006 [Abstract] [Full Text] [PDF]  

Barry P. McMahon, Jens B. Frøkjær, Peter Kunwald, Donghua Liao, Peter Funch-Jensen, Asbjørn M. Drewes, and Hans Gregersen

The functional lumen imaging probe (FLIP) for evaluation of the esophagogastric junction
Am J Physiol Gastrointest Liver Physiol 292: G377-G384, 2007. First published August 31, 2006; doi:10.1152/ajpgi.00311.2006 [Abstract] [Full Text] [PDF]  

Bruce A. Vallance, Nicola Radojevic, Cory M. Hogaboam, Yikang Deng, Jack Gauldie, and Stephen M. Collins

IL-4 gene transfer to the small bowel serosa leads to intestinal inflammation and smooth muscle hyperresponsiveness
Am J Physiol Gastrointest Liver Physiol 292: G385-G394, 2007; doi:10.1152/ajpgi.00065.2006 [Abstract] [Full Text] [PDF]  

Ping Cong, Zuo-Liang Xiao, Piero Biancani, and Jose Behar

Prostaglandins mediate tonic contraction of the guinea pig and human gallbladder
Am J Physiol Gastrointest Liver Physiol 292: G409-G418, 2007. First published June 8, 2006; doi:10.1152/ajpgi.00091.2006 [Abstract] [Full Text] [PDF]  

LIVER AND BILIARY TRACT:

Masahiro Iizuka, Kenji Sasaki, Yohei Hirai, Kenichi Shindo, Shiho Konno, Hiroaki Itou, Shigetoshi Ohshima, Yasuo Horie, and Sumio Watanabe

Morphogenic protein epimorphin protects intestinal epithelial cells from oxidative stress by the activation of EGF receptor and MEK/ERK, PI3 kinase/Akt signals
Am J Physiol Gastrointest Liver Physiol 292: G39-G52, 2007. First published August 3, 2006; doi:10.1152/ajpgi.00181.2006 [Abstract] [Full Text] [PDF]  

Satoshi Kuboki, Tomohisa Okaya, Rebecca Schuster, John Blanchard, Alvin Denenberg, Hector R. Wong, and Alex B. Lentsch

Hepatocyte NF-B activation is hepatoprotective during ischemia-reperfusion injury and is augmented by ischemic hypothermia
Am J Physiol Gastrointest Liver Physiol 292: G201-G207, 2007. First published August 31, 2006; doi:10.1152/ajpgi.00186.2006 [Abstract] [Full Text] [PDF]  

Beat M. Künzli, Pascal O. Berberat, Thomas Giese, Eva Csizmadia, Elzbieta Kaczmarek, Colin Baker, Irfan Halaceli, Markus W. Büchler, Helmut Friess, and Simon C. Robson

Upregulation of CD39/NTPDases and P2 receptors in human pancreatic disease
Am J Physiol Gastrointest Liver Physiol 292: G223-G230, 2007. First published August 17, 2006; doi:10.1152/ajpgi.00259.2006 [Abstract] [Full Text] [PDF]  

Rana Dajani, Salih Sanlioglu, Yulong Zhang, Qiang Li, Martha M. Monick, Eric Lazartigues, Timothy Eggleston, Robin L. Davisson, Gary W. Hunninghake, and John F. Engelhardt

Pleiotropic functions of TNF- determine distinct IKK-dependent hepatocellular fates in response to LPS
Am J Physiol Gastrointest Liver Physiol 292: G242-G252, 2007. First published August 24, 2006; doi:10.1152/ajpgi.00043.2006 [Abstract] [Full Text] [PDF]  

Ardeshir Z. Hashmi, Wyel Hakim, Emma A. Kruglov, Azuma Watanabe, William Watkins, Jonathan A. Dranoff, and Wajahat Z. Mehal

Adenosine inhibits cytosolic calcium signals and chemotaxis in hepatic stellate cells
Am J Physiol Gastrointest Liver Physiol 292: G395-G401, 2007. First published October 19, 2006; doi:10.1152/ajpgi.00208.2006 [Abstract] [Full Text] [PDF]  

Elangovan Gopal, Seiji Miyauchi, Pamela M. Martin, Sudha Ananth, Sonne R. Srinivas, Sylvia B. Smith, Puttur D. Prasad, and Vadivel Ganapathy

Expression and functional features of NaCT, a sodium-coupled citrate transporter, in human and rat livers and cell lines
Am J Physiol Gastrointest Liver Physiol 292: G402-G408, 2007. First published September 14, 2006; doi:10.1152/ajpgi.00371.2006 [Abstract] [Full Text] [PDF]  

REPORTS:

L. Wang, V. Martínez, H. Kimura, and Y. Taché

5-Hydroxytryptophan activates colonic myenteric neurons and propulsive motor function through 5-HT₄ receptors in conscious mice
Am J Physiol Gastrointest Liver Physiol 292: G419-G428, 2007. First published September 21, 2006; doi:10.1152/ajpgi.00289.2006 [Abstract] [Full Text] [PDF]  

J. R. Grider and B. E. Piland

The peristaltic reflex induced by short-chain fatty acids is mediated by sequential release of 5-HT and neuronal CGRP but not BDNF
Am J Physiol Gastrointest Liver Physiol 292: G429-G437, 2007. First published September 14, 2006; doi:10.1152/ajpgi.00376.2006 [Abstract] [Full Text] [PDF]  

Ching-Liang Lu, Jen-Chuen Hsieh, Meei-Ling Tsaur, Yn-Ho Huang, Paulus S. Wang, Learn-Long Wu, Pei-Yi Liu, Full-Young Chang, and Shou-Dong Lee

Estrogen rapidly modulates mustard oil-induced visceral hypersensitivity in conscious female rats: a role of CREB phosphorylation in spinal dorsal horn neurons
Am J Physiol Gastrointest Liver Physiol 292: G438-G446, 2007. First published September 14, 2006; doi:10.1152/ajpgi.00210.2006 [Abstract] [Full Text] [PDF]  

Hiroshi Ishiguro, Wan Namkung, Akiko Yamamoto, Zhaohui Wang, Roger T. Worrell, Jie Xu, Min Goo Lee, and Manoocher Soleimani

Effect of Slc26a6 deletion on apical Cl^–/HCO₃^– exchanger activity and cAMP-stimulated bicarbonate secretion in pancreatic duct
Am J Physiol Gastrointest Liver Physiol 292: G447-G455, 2007. First published August 10, 2006; doi:10.1152/ajpgi.00286.2006 [Abstract] [Full Text] [PDF]  

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