THEMES:

David Y. Hui, Eric D. Labonté, and Philip N. Howles

Development and Physiological Regulation of Intestinal Lipid Absorption. III. Intestinal transporters and cholesterol absorption
Am J Physiol Gastrointest Liver Physiol 294: G839-G843, 2008. First published February 14, 2008; doi:10.1152/ajpgi.00061.2008 [Abstract] [Full Text] [PDF]  

Shohreh F. Farzan, Samer Singh, Neal S. Schilling, and David J. Robbins

The Adventures of Sonic Hedgehog in Development and Repair. III. Hedgehog processing and biological activity
Am J Physiol Gastrointest Liver Physiol 294: G844-G849, 2008. First published January 31, 2008; doi:10.1152/ajpgi.00564.2007 [Abstract] [Full Text] [PDF]  

Pál Pacher and Bin Gao

Endocannabinoids and Liver Disease. III. Endocannabinoid effects on immune cells: implications for inflammatory liver diseases
Am J Physiol Gastrointest Liver Physiol 294: G850-G854, 2008. First published January 31, 2008; doi:10.1152/ajpgi.00523.2007 [Abstract] [Full Text] [PDF]  

MUCOSAL BIOLOGY:

Rijin Xiao, Ying Su, Rosalia C. M. Simmen, and Frank A. Simmen

Dietary soy protein inhibits DNA damage and cell survival of colon epithelial cells through attenuated expression of fatty acid synthase
Am J Physiol Gastrointest Liver Physiol 294: G868-G876, 2008. First published January 31, 2008; doi:10.1152/ajpgi.00515.2007 [Abstract] [Full Text] [PDF]  

James F. Collins, Zihua Hu, P. N. Ranganathan, Dian Feng, Laura M. Garrick, Michael D. Garrick, and Richard W. Browne

Induction of arachidonate 12-lipoxygenase (Alox15) in intestine of iron-deficient rats correlates with the production of biologically active lipid mediators
Am J Physiol Gastrointest Liver Physiol 294: G948-G962, 2008. First published February 7, 2008; doi:10.1152/ajpgi.00274.2007 [Abstract] [Full Text] [PDF] [Supplemental Tables]  

Satish Ramalingam, Gopalan Natarajan, Chris Schafer, Dharmalingam Subramaniam, Randal May, Ilangovan Ramachandran, Lurdes Queimado, Courtney W. Houchen, and Shrikant Anant

Novel intestinal splice variants of RNA-binding protein CUGBP2: isoform-specific effects on mitotic catastrophe
Am J Physiol Gastrointest Liver Physiol 294: G971-G981, 2008. First published February 7, 2008; doi:10.1152/ajpgi.00540.2007 [Abstract] [Full Text] [PDF]  

Dharmalingam Subramaniam, Gopalan Natarajan, Satish Ramalingam, Ilangovan Ramachandran, Randal May, Lurdes Queimado, Courtney W. Houchen, and Shrikant Anant

Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein CUGBP2
Am J Physiol Gastrointest Liver Physiol 294: G1025-G1032, 2008. First published February 21, 2008; doi:10.1152/ajpgi.00602.2007 [Abstract] [Full Text] [PDF]  

A. Seth, Fang Yan, D. Brent Polk, and R. K. Rao

Probiotics ameliorate the hydrogen peroxide-induced epithelial barrier disruption by a PKC- and MAP kinase-dependent mechanism
Am J Physiol Gastrointest Liver Physiol 294: G1060-G1069, 2008. First published February 21, 2008; doi:10.1152/ajpgi.00202.2007 [Abstract] [Full Text] [PDF]  

Adam T. Stearns, Anita Balakrishnan, Jan Rounds, David B. Rhoads, Stanley W. Ashley, and Ali Tavakkolizadeh

Capsaicin-sensitive vagal afferents modulate posttranscriptional regulation of the rat Na⁺/glucose cotransporter SGLT1
Am J Physiol Gastrointest Liver Physiol 294: G1078-G1083, 2008. First published February 28, 2008; doi:10.1152/ajpgi.00591.2007 [Abstract] [Full Text] [PDF]  

INFLAMMATION/IMMUNITY/MEDIATORS:

Masaharu Mita, Masahiko Satoh, Akinori Shimada, Mina Okajima, Sadahiro Azuma, Junko S. Suzuki, Kou Sakabe, Shuntaro Hara, and Seiichiro Himeno

Metallothionein is a crucial protective factor against Helicobacter pylori-induced gastric erosive lesions in a mouse model
Am J Physiol Gastrointest Liver Physiol 294: G877-G884, 2008. First published January 31, 2008; doi:10.1152/ajpgi.00251.2007 [Abstract] [Full Text] [PDF]  

Francesco Raimondi, Pasquale Santoro, Maria Vittoria Barone, Serena Pappacoda, Maria Luisa Barretta, Merlin Nanayakkara, Carmela Apicella, Letizia Capasso, and Roberto Paludetto

Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation
Am J Physiol Gastrointest Liver Physiol 294: G906-G913, 2008. First published January 31, 2008; doi:10.1152/ajpgi.00043.2007 [Abstract] [Full Text] [PDF]  

Walter Fries, Carmelo Muja, Carmela Crisafulli, Salvatore Cuzzocrea, and Emanuela Mazzon

Dynamics of enterocyte tight junctions: effect of experimental colitis and two different anti-TNF strategies
Am J Physiol Gastrointest Liver Physiol 294: G938-G947, 2008. First published February 7, 2008; doi:10.1152/ajpgi.00469.2007 [Abstract] [Full Text] [PDF]  

HORMONES AND SIGNALING:

Jimmy Y. C. Chow, Hui Dong, Khai T. Quach, Phuoc Nam Van Nguyen, Kevin Chen, and John M. Carethers

TGF-β mediates PTEN suppression and cell motility through calcium-dependent PKC- activation in pancreatic cancer cells
Am J Physiol Gastrointest Liver Physiol 294: G899-G905, 2008. First published January 31, 2008; doi:10.1152/ajpgi.00411.2007 [Abstract] [Full Text] [PDF]  

Shi Jin, Ramesh M. Ray, and Leonard R. Johnson

TNF-/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species
Am J Physiol Gastrointest Liver Physiol 294: G928-G937, 2008. First published January 24, 2008; doi:10.1152/ajpgi.00219.2007 [Abstract] [Full Text] [PDF]  

NEUROREGULATION AND MOTILITY:

Nick J. Spencer, Aoife Kerrin, Vladimir P. Zagorodnyuk, Grant W. Hennig, Melodie Muto, Simon J. Brookes, and Orla McDonnell

Identification of functional intramuscular rectal mechanoreceptors in aganglionic rectal smooth muscle from piebald lethal mice
Am J Physiol Gastrointest Liver Physiol 294: G855-G867, 2008. First published January 24, 2008; doi:10.1152/ajpgi.00502.2007 [Abstract] [Full Text] [PDF]  

Lilani Perera, Mark Kern, Candy Hofmann, Linda Tatro, Krisna Chai, Shiko Kuribayashi, Adeyemi Lawal, and Reza Shaker

Manometric evidence for a phonation-induced UES contractile reflex
Am J Physiol Gastrointest Liver Physiol 294: G885-G891, 2008. First published January 31, 2008; doi:10.1152/ajpgi.00470.2007 [Abstract] [Full Text] [PDF]  

Philip J. Matthews, Charles H. Knowles, Yang C. Chua, Claire Delaney, Anthony R. Hobson, and Qasim Aziz

Effects of the concentration and frequency of acid infusion on the development and maintenance of esophageal hyperalgesia in a human volunteer model
Am J Physiol Gastrointest Liver Physiol 294: G914-G917, 2008. First published February 7, 2008; doi:10.1152/ajpgi.00445.2007 [Abstract] [Full Text] [PDF]  

Xiaoyin Wu, Jun Gao, Jin Yan, Jing Fan, Chung Owyang, and Ying Li

Role for NMDA receptors in visceral nociceptive transmission in the anterior cingulate cortex of viscerally hypersensitive rats
Am J Physiol Gastrointest Liver Physiol 294: G918-G927, 2008. First published February 7, 2008; doi:10.1152/ajpgi.00452.2007 [Abstract] [Full Text] [PDF]  

Amanda J. Page, Tracey A. O'Donnell, and L. Ashley Blackshaw

Opioid modulation of ferret vagal afferent mechanosensitivity
Am J Physiol Gastrointest Liver Physiol 294: G963-G970, 2008. First published February 7, 2008; doi:10.1152/ajpgi.00562.2007 [Abstract] [Full Text] [PDF]  

Michal M. Szczesniak, Sergio E. Fuentealba, Anthea Burnett, and Ian J. Cook

Differential relaxation and contractile responses of the human upper esophageal sphincter mediated by interplay of mucosal and deep mechanoreceptor activation
Am J Physiol Gastrointest Liver Physiol 294: G982-G988, 2008. First published February 7, 2008; doi:10.1152/ajpgi.00496.2007 [Abstract] [Full Text] [PDF]  

Alberto Corrias and Martin L. Buist

Quantitative cellular description of gastric slow wave activity
Am J Physiol Gastrointest Liver Physiol 294: G989-G995, 2008. First published February 14, 2008; doi:10.1152/ajpgi.00528.2007 [Abstract] [Full Text] [PDF]  

Rachael R. Roberts, Joel C. Bornstein, Annette J. Bergner, and Heather M. Young

Disturbances of colonic motility in mouse models of Hirschsprung's disease
Am J Physiol Gastrointest Liver Physiol 294: G996-G1008, 2008. First published February 14, 2008; doi:10.1152/ajpgi.00558.2007 [Abstract] [Full Text] [PDF]  

Muriel Larauche, Sylvie Bradesi, Mulugeta Million, Peter McLean, Yvette Taché, Emeran A. Mayer, and James A. McRoberts

Corticotropin-releasing factor type 1 receptors mediate the visceral hyperalgesia induced by repeated psychological stress in rats
Am J Physiol Gastrointest Liver Physiol 294: G1033-G1040, 2008. First published February 28, 2008; doi:10.1152/ajpgi.00507.2007 [Abstract] [Full Text] [PDF]  

Bronagh McDonnell, Ross Hamilton, Miranda Fong, Sean M. Ward, and Kathleen D. Keef

Functional evidence for purinergic inhibitory neuromuscular transmission in the mouse internal anal sphincter
Am J Physiol Gastrointest Liver Physiol 294: G1041-G1051, 2008. First published February 28, 2008; doi:10.1152/ajpgi.00356.2007 [Abstract] [Full Text] [PDF]  

Renta Katsui, Yu Kojima, Hiroki Kuniyasu, Juichiro Shimizu, Fumikazu Koyama, Hisao Fujii, Yoshiyuki Nakajima, and Miyako Takaki

A new possibility for repairing the anal dysfunction by promoting regeneration of the reflex pathways in the enteric nervous system
Am J Physiol Gastrointest Liver Physiol 294: G1084-G1093, 2008. First published February 28, 2008; doi:10.1152/ajpgi.00345.2007 [Abstract] [Full Text] [PDF]  

Yusnita Rifai, Alison S. F. Elder, Colin J. Carati, Damian J. Hussey, Xin Li, Charmaine M. Woods, Ann C. Schloithe, Anthony C. Thomas, Ronald D. Mathison, Joseph S. Davison, James Toouli, and Gino T. P. Saccone

The tripeptide analog feG ameliorates severity of acute pancreatitis in a caerulein mouse model
Am J Physiol Gastrointest Liver Physiol 294: G1094-G1099, 2008. First published February 28, 2008; doi:10.1152/ajpgi.00534.2007 [Abstract] [Full Text] [PDF]  

LIVER AND BILIARY TRACT:

Min You, Xiaomei Liang, Joanne M. Ajmo, and Gene C. Ness

Involvement of mammalian sirtuin 1 in the action of ethanol in the liver
Am J Physiol Gastrointest Liver Physiol 294: G892-G898, 2008. First published January 31, 2008; doi:10.1152/ajpgi.00575.2007 [Abstract] [Full Text] [PDF]  

Clavia Ruth Wooton-Kee, David E. Cohen, and Mary Vore

Increased cholesterol 7-hydroxylase expression and size of the bile acid pool in the lactating rat
Am J Physiol Gastrointest Liver Physiol 294: G1009-G1016, 2008. First published February 21, 2008; doi:10.1152/ajpgi.00017.2008 [Abstract] [Full Text] [PDF]  

Anthony R. Sheets, Péter Fülöp, Zoltán Derdák, Andrea Kassai, Edmond Sabo, Nicholas M. Mark, György Paragh, Jack R. Wands, and György Baffy

Uncoupling protein-2 modulates the lipid metabolic response to fasting in mice
Am J Physiol Gastrointest Liver Physiol 294: G1017-G1024, 2008. First published February 21, 2008; doi:10.1152/ajpgi.00016.2008 [Abstract] [Full Text] [PDF]  

Pijun Wang, Soichiro Hata, Yansen Xiao, John W. Murray, and Allan W. Wolkoff

Topological assessment of oatp1a1: a 12-transmembrane domain integral membrane protein with three N-linked carbohydrate chains
Am J Physiol Gastrointest Liver Physiol 294: G1052-G1059, 2008. First published February 28, 2008; doi:10.1152/ajpgi.00584.2007 [Abstract] [Full Text] [PDF]  

Kezhen Shen, Shu-Sen Zheng, Ogyi Park, Hua Wang, Zhaoli Sun, and Bin Gao

Activation of innate immunity (NK/IFN-) in rat allogeneic liver transplantation: contribution to liver injury and suppression of hepatocyte proliferation
Am J Physiol Gastrointest Liver Physiol 294: G1070-G1077, 2008. First published February 21, 2008; doi:10.1152/ajpgi.00554.2007 [Abstract] [Full Text] [PDF]  

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